Through his work, Elgendy will investigate the estrogen-related receptor alpha (ERRα) and the critical role it plays in regulating genes involved in oxidative stress and inflammation. Elgendy’s research will work to develop first-in-class chemical probes to validate ERRa as a potential target for Alzheimer’s and other neurodegenerative disorders.
Elgendy is serving as principal investigator on the project and will be supported by Dr. Tom Burris who will serve as co-investigator.