Bahaa Elgendy, Ph.D., assistant professor of medicinal chemistry at University of Health Sciences and Pharmacy in St. Louis, was the lead author of a recent article featured in the Journal of Medicinal Chemistry’s Perspective series. The series provides a forum for recognized research experts to review and provide their input on active areas of research.
Elgendy worked to develop the article alongside Yuanying Fang, Ph.D., associate professor at the Jiangxi University of Traditional Chinese Medicine and former postdoctoral research associate in the Elgendy lab at the Center for Clinical Pharmacology; Lamees Hegazy, Ph.D., assistant professor of medicinal chemistry at UHSP and Brian N. Finck, Ph.D., professor of medicine at Washington University School of Medicine in St. Louis. The article focused on the Farnesoid X receptor (FXR), which is an important regulator of bile acid, lipid, amino acid, glucose homeostasis, hepatic inflammation, regeneration and fibrosis.